Influenza Pandemic … further thoughts:
By Doctor Tom on April 30, 2009 at 2:35 AM in Current Affairs, Health Care, Influenza Pandemic
(Bumped up from Wednesday morning.)
Thanks to all who responded to my piece regarding the administration response to this pandemic of influenza. As I go through the news sources today, there really isn’t much exciting unless one examines the response of the locals. What I am seeing is an admirable effort to educate the public in the lay press and an immediate and rather thorough communication to the physician community regarding this illness. This includes methods of identifying suspicious cases, actions to take in response to identification of suspicious cases, and an effort to collect blood to serologically track this disease.
The ‘alarm’ I was talking about has been sounded. This illness must be approached with more than concern; markedly heightened awareness bordering on alarm would be a more effective attitude.
For instance, in Nebraska, the Dept. of Health has e-mailed all physicians with reminders of identifying features of patients who may suffer this illness and recommendations regarding the handling of these persons. This includes the immediate masking of persons with suspicious symptoms, masking of health care delivery personel, isolation of the patient, hand washing, and collection of appropriate blood samples. The news media has published very nice explanations of the varying symptoms of influenza-like illnesses so that the public knows what to expect and how to respond. I am impressed with the local responses.
I am also impressed that I heard nothing stupid from the government today. Did they read my criticism previously published? I’m sorry…sometimes I imagine stuff. Hopefully, they realized that the CDC efforts and the local efforts were more appropriate than our President’s previous unintelligent responses.
In answer to those respondants who drew comparisons of past ‘epidemics’ and scares. Viruses are an enteresting group of biologic molecules; there is even debate as to whether they constitute a life-form. Most scientists do consider them ‘life’ since they replicate, but they, themselves don’t have a specific metabolic machinery. They are extraordinarily efficient parasites….that is, they replicate only in biologic cells for the most part. The scary part is that they can adapt. They can mutate as all DNA and RNA material may and some of those mutations may be more resistant to anti-viral drugs, more infectious than their forebears, or just plain more destructive to the cells they infect. As a rule, viruses either destroy or severely damage the cells they infect and subsequently multiply within; and they multiply by using that cell to make millions of copies of themselves. That is, until our immune system figures out there is a foreign invader and produces enough antibody to neutralize the viral particles rendering them non-infective. One of the reasons HIV is so resistant to treatment is that it infects the very cells that direct effective immune responses against foreign organisms including viruses.
One of the largest dangers in viral infections…and the one which sparks the interest of virologists with this one…is that ability of the virus to morph into a form that is different than previously experienced. Influenza does this on a regular basis, year by year. This is the frightening fact: what if the virus morphed into a really virulent form once again…and is this current pandemic indicative of that. At this time, I don’t think there is an answer to this. Time will tell. But, this is the cause for heightened concern bordering on ‘alarm’. This particular virus has popped up pretty fast simultaneously in a number of spots world-wide and has appeared to manifest enhanced virulence and a poorer outcome than past epidemics. Usually, the mortality associated with influenza is due to the secondary infections that develop because of the damage to the respiratory system, the debilitation of a more prolonged illness, or acute cardiac events as a result of the stress of the illness in those at risk . Once the score is recorded in this pandemic we will know far more about this particular virus.
My point is simply that when dealing with a suddenly more virulent viral infection, it is inappropriate to panic, but it is also completely irresponsible to repress markedly heightened diligence. People should be informed to be alert, observant, and worried. Not paralyzingly worried, but worried enough that common-sense measures become more important; hand-washing, not ignoring febrile upper respiratory illnesses, reporting these illnesses to their physicians, and segregation of ill persons from the populace until they begin to recover. In addition, those who are suggesting travel to Mexico (for instance) is ill-advised, are absolutely worth heeding. This appears to be an area heavily affected and to travel to that area at this time seems foolhardy.
Hopefully our administration will continue to let the experts and the local health officials continue to put forth what seems to have been an effective strategy. Politics has no place in this arena….none, whatsoever. I’m holding my breath; the track record of politicians in affairs they have no business interfering in is dismal. I hope this post answered some of the questions in the queries of the prior article. By the way, one of the best educational sources regarding this subject in general is Scientific American magazine which can be accessed on the internet (Sciam.com).
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Dr. Sears, a cardiologist, is Larry Johnson’s brother-in-law.

















